Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756660 | 0.98 | ALDH1A1 (0.39) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7758039 | 0.94 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7756102 | 0.92 | LMNA (0.45) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7752017 | 0.92 | LMNA (0.45) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7752033 | 0.92 | LMNA (0.45) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7752149 | 0.90 | LMNA (0.48) | ALDH1A1LMNAGPR84CA2FFAR1 | |
| SCHEMBL7752021 | 0.89 | ALDH1A1 (0.33) | ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL7756148 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL7752041 | 0.88 | CYP3A4 (0.33) | ALDH1A1LMNACYP3A4MAPT | |
| SCHEMBL7756128 | 0.88 | CYP3A4 (0.33) | ALDH1A1LMNACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |