Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752041 | 1.00 | CYP3A4 (0.33) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL7752021 | 0.98 | ALDH1A1 (0.33) | CYP3A4ALDH1A1LMNA | |
| SCHEMBL7754864 | 0.94 | LMNA (0.36) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL7755407 | 0.94 | LMNA (0.36) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL7756115 | 0.93 | ALDH1A1 (0.34) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL8757628 | 0.93 | ALDH1A1 (0.34) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL7754014 | 0.92 | LMNA (0.37) | CYP3A4ALDH1A1LMNAMEN1THRB | |
| SCHEMBL7755400 | 0.92 | ALDH1A1 (0.35) | CYP3A4ALDH1A1LMNA | |
| SCHEMBL9073883 | 0.90 | LMNA (0.42) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL7755395 | 0.90 | LMNA (0.42) | LMNAMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |