Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088989 | 0.90 | ALOX15 (0.41) | CHRM2CHRM1ALOX15MEN1KMT2A | |
| SCHEMBL7754999 | 0.82 | CHRM2 (0.51) | CHRM2CHRM1ALOX15KMT2A | |
| SCHEMBL4661558 | 0.80 | CHRM2 (0.48) | CHRM2CHRM1ALOX15MEN1KMT2A | |
| SCHEMBL2166654 | 0.80 | CHRM2 (0.61) | CHRM2CHRM1PTGS1 | |
| SCHEMBL15559016 | 0.79 | THRA (0.34) | CHRM2CHRM1PTGS1KMT2A | |
| SCHEMBL3774216 | 0.79 | AKR1C3 (0.33) | — | |
| SCHEMBL4659057 | 0.77 | CHRM2 (0.62) | CHRM2CHRM1ALOX15KMT2A | |
| SCHEMBL1158251 | 0.77 | CHRM2 (0.62) | CHRM2CHRM1ALOX15KMT2A | |
| SCHEMBL6539682 | 0.76 | CHRM2 (0.39) | CHRM2CHRM1ALOX15PTGS1MEN1 | |
| SCHEMBL7755051 | 0.76 | CHRM2 (0.39) | CHRM2CHRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |