Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772904 | 0.89 | ALOX15 (0.41) | CHRM2CHRM1KMT2AMEN1FAAH | |
| SCHEMBL2166654 | 0.81 | CHRM2 (0.61) | CHRM2CHRM1PTGS1FAAHMGLL | |
| SCHEMBL6761854 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1KMT2AMEN1CYP3A4 | |
| SCHEMBL6757054 | 0.81 | CHRM2 (0.52) | CHRM2CHRM1KMT2AMEN1ELANE | |
| SCHEMBL6760711 | 0.80 | CHRM2 (0.42) | CHRM2CHRM1KMT2AELANEALDH1A1 | |
| SCHEMBL3779737 | 0.79 | ELANE (0.44) | CHRM2CHRM1ELANECYP3A4ALDH1A1 | |
| SCHEMBL7755039 | 0.76 | CHRM2 (0.38) | CHRM2CHRM1KMT2AMEN1PTGS1 | |
| SCHEMBL6760480 | 0.74 | CHRM2 (0.51) | CHRM2CHRM1KMT2AMEN1ELANE | |
| SCHEMBL6539686 | 0.72 | HPGD (0.31) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL8096707 | 0.71 | LMNA (0.37) | CHRM2CHRM1KMT2ACYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG | 2004-09-23 | — | — | US | disclosed |
| US-6713464-B1 | ANTIMUSCARINIC AGENTS WITH SUPERIOR PHARMACOKINETICS | SCHWARZ PHARMA AG (DE) | 2004-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | ADRB3, ADRA1D, TNNC1 | CHRM2 136/4885CHRM1 227/4885KMT2A 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.