Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022484 | 0.90 | HDAC4 (0.43) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7025463 | 0.86 | HDAC4 (0.44) | HDAC4HDAC7HDAC5RECQLKDM4E | |
| SCHEMBL8332615 | 0.86 | HDAC4 (0.36) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7755161 | 0.81 | HDAC4 (0.42) | HDAC4HDAC7HDAC5RECQLALDH1A1 | |
| SCHEMBL8686343 | 0.81 | MAPK1 (0.35) | HDAC4HDAC7HDAC5KMT2AALDH1A1 | |
| SCHEMBL5161928 | 0.79 | HDAC4 (0.47) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7755709 | 0.79 | HDAC4 (0.44) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| Trifluoromethanesulfonic Acid SCHEMBL7030203 | 0.78 | HDAC4 (0.39) | TP53HDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL7024113 | 0.78 | IDO1 (0.36) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL5705454 | 0.77 | HDAC4 (0.43) | HDAC4HDAC7HDAC5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755457-B1 | Novel Aryl-N-Alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection | LUMIGEN INC (US) | 2001-02-21 | — | — | EP | claimed |
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | claimed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | claimed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | claimed |
| EP-0755457-B1 | Novel Aryl-N-Alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection | LUMIGEN INC (US) | 2001-02-21 | — | — | EP | disclosed |
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |