SCHEMBL7755231

SCHEMBL7755231

CC(=O)OCc1cc(-c2ccccc2)n(C)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 8/20 0.47
ALDH1A1 P00352 1/20 0.46
NR1H4 Q96RI1 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
SLC16A1 P53985 6/20 0.43
MCTS1 Q9ULC4 5/20 0.42
GRM5 P41594 1/20 0.41
PTGS2 P35354 2/20 0.40
PTGS1 P23219 1/20 0.39
IDH1 O75874 1/20 0.39
MPO P05164 1/20 0.38
NPC1 O15118 1/20 0.38
ALPL P05186 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752681 0.82 SLC16A3 (0.42) SLC16A3ALDH1A1NR1H4CYP1A2CYP2C9
SCHEMBL3549297 0.82 GRM5 (0.39) SLC16A3ALDH1A1NR1H4MEN1KMT2A
SCHEMBL22912537 0.80 POLB (0.43) SLC16A3ALDH1A1NR1H4MEN1KMT2A
SCHEMBL5966699 0.78 KDM4E (0.49) ALDH1A1NR1H4MEN1KMT2ACYP1A2
SCHEMBL27046141 0.78 SLC16A3 (0.41) SLC16A3ALDH1A1NR1H4SLC16A1MCTS1
SCHEMBL1779503 0.77 PTGS2 (0.52) SLC16A3NR1H4GRM5PTGS2MPO
SCHEMBL24408917 0.76 NR1H4 (0.54) ALDH1A1NR1H4MEN1KMT2APTGS1
SCHEMBL10275017 0.75 CNR1 (0.45) ALDH1A1NR1H4KMT2AGRM5PTGS2
SCHEMBL27517063 0.75 MAPT (0.43) ALDH1A1NR1H4GRM5NPC1
SCHEMBL15677567 0.74 SLC16A3 (0.50) SLC16A3NR1H4SLC16A1MCTS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 EP claimed
EP-0808308-B1 METHOD FOR SEPARATING CARBINOLS ESTEVE LABOR DR (ES) 2001-03-07 EP disclosed
EP-0808308-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-11-26 EP disclosed
WO-1997020817-A1 METHOD FOR SEPARATING CARBINOLS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1997-06-12 WO disclosed