Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756612 | 0.98 | LMNA (0.44) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7754325 | 0.94 | TSHR (0.41) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7770458 | 0.90 | LMNA (0.44) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7755108 | 0.90 | MEN1 (0.42) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7756678 | 0.88 | MEN1 (0.45) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL7753968 | 0.88 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1CNR1CNR2LMNA | |
| SCHEMBL23501872 | 0.87 | LPAR3 (0.41) | ALDH1A1CNR1CNR2LPAR1LPAR2 | |
| SCHEMBL23501869 | 0.87 | LPAR3 (0.41) | ALDH1A1CNR1CNR2LPAR1LPAR2 | |
| SCHEMBL9491967 | 0.86 | MGLL (0.47) | ALDH1A1CNR1CNR2MEN1KMT2A | |
| SCHEMBL25228930 | 0.85 | LPAR2 (0.48) | LPAR1LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835248-B1 | 1-AMINO-3-BENZYLURACILS | BASF AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |