Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422524 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| Hydrochloric Acid SCHEMBL7571169 | 0.92 | FBP1 (0.47) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| SCHEMBL5564527 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| SCHEMBL9822669 | 0.85 | MMP2 (0.45) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| SCHEMBL56599 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| SCHEMBL9822643 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HSD17B10TDP1PGRMEN1 | |
| SCHEMBL2199161 | 0.83 | AKR1B1 (0.56) | ALDH1A1PGRMEN1KMT2AMMP2 | |
| SCHEMBL31435391 | 0.83 | AKR1B1 (0.56) | ALDH1A1PGRMEN1KMT2AMMP2 | |
| SCHEMBL294450 | 0.81 | PGR (0.53) | ALDH1A1TDP1PGRMEN1KMT2A | |
| SCHEMBL294451 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TDP1PGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010846-A | 1-Phenyl-1H-benzo [ d ] imidazole compound serving as FLT3 kinase inhibitor, preparation method, pharmaceutical composition and application | 天津医科大学 | 2026-05-12 | — | — | CN | claimed |
| CN-119425423-A | Positively charged composite membrane and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118406235-A | High-temperature-resistant polyarylsulfone resin and preparation method thereof | 吉林大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118388767-A | Semi-crystalline copolymerized polyarylethersulfone and preparation method thereof | 吉林大学 | 2024-07-26 | — | — | CN | claimed |
| CN-118084792-A | Pyrazole-5-sulfonamide derivative, and preparation method and application thereof | 安徽农业大学 | 2024-05-28 | — | — | CN | claimed |
| CN-114195433-B | Environment-friendly waterproof material for buildings | 河南兰堡湾涂料科技有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-114349409-A | Composite material for building and preparation method thereof | 湖北淇源新材料科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-114195433-A | Environment-friendly waterproof material for buildings | 湖北淇源新材料科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-111472019-A | Synthesis method of N-sulfonyl azole compound | 安阳师范学院 | 2020-07-31 | — | — | CN | claimed |
| CN-107540691-A | Using diaryl ether as Macrocyclic lactams compound of skeleton and preparation method thereof | 上海药明康德新药开发有限公司 | 2018-01-05 | — | — | CN | claimed |
| EP-2385831-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | The UAB Research Foundation (US) | 2011-11-16 | — | — | EP | claimed |
| US-20110254866-A1 | INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE | SONY CORPORATION (JP) | 2011-10-20 | — | — | US | claimed |
| WO-2010123591-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | WO | claimed |
| CN-101384579-A | Selective n-sulfonylation of 2-amino trifluoroalkyl substituted alcohols | WYETH CORP (US) | 2009-03-11 | — | — | CN | claimed |
| EP-1984347-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | Wyeth a Corporation of the State of Delaware (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2007098030-A1 | SELECTIVE N-SULFONYLATION OF 2-AMINO TRIFLUOROALKYL SUBSTITUTED ALCOHOLS | WYETH (US) | 2007-08-30 | — | — | WO | claimed |
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | WYETH (US) | 2007-08-23 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-4880576-A | HALOGENATION OF ACIDS, FORMAMIDE CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | claimed |
| US-4012442-A | FRIEDEL-CRAFTS CATALYST, BENZENE SULFONYL CHLORIDE, CHLORINE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197800-A1 | Selective n-sulfonylation of 2-amino flouro-and trifluoroalkyl substituted alcohols | BRAF, AFF2, SELENOI | ALDH1A1 1532/4885HSD17B10 4189/4885TDP1 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.