Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661559 | 0.90 | ALOX15 (0.41) | ALOX15MTNR1AAKR1C3AKR1C2PPARA | |
| SCHEMBL3774216 | 0.89 | AKR1C3 (0.33) | AKR1C3AKR1C2FAAHMGLLPTGER1 | |
| SCHEMBL7755007 | 0.86 | ADRB2 (0.41) | ALOX15MTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL7755600 | 0.85 | ALOX15 (0.42) | ALOX15MTNR1AAKR1C3AKR1C2FAAH | |
| SCHEMBL3772824 | 0.84 | ADRB2 (0.40) | ALOX15MTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL7755565 | 0.83 | SLC6A2 (0.41) | ADRB2 | |
| SCHEMBL7758293 | 0.82 | ELANE (0.38) | MTNR1APPARGPPARAADRB2ADRA2A | |
| SCHEMBL15541962 | 0.82 | APP (0.37) | FAAHMGLLPTGER1PTGER4PTGER3 | |
| SCHEMBL1158253 | 0.81 | CHRM2 (0.45) | ALOX15PPARAADRB2ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL16166428 | 0.80 | CHRM2 (0.45) | ALOX15PPARAADRB2ADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |