Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772824 | 0.87 | ADRB2 (0.40) | AKT1MTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL7755059 | 0.85 | ELANE (0.44) | ELANECHRM2CHRM1ADRB2PPARA | |
| SCHEMBL7758290 | 0.85 | ELANE (0.42) | ELANEAKT1CHRM2CHRM1PPARA | |
| SCHEMBL7755007 | 0.85 | ADRB2 (0.41) | AKT1MTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL7755565 | 0.82 | SLC6A2 (0.41) | ADRB2KDM4EALDH1A1 | |
| SCHEMBL7755603 | 0.82 | ALOX15 (0.40) | MTNR1AADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL11296010 | 0.80 | ALDH1A1 (0.38) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1158253 | 0.80 | CHRM2 (0.45) | AKT1MTNR1BCHRM2CHRM1ADRB2 | |
| SCHEMBL4660298 | 0.80 | PTGS2 (0.44) | AKT1CHRM2CHRM1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL16166428 | 0.79 | CHRM2 (0.45) | AKT1MTNR1BCHRM2CHRM1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |