Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414155 | 0.89 | IDO1 (0.53) | TTRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL11124814 | 0.89 | IDO1 (0.53) | TTRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL10647420 | 0.88 | SLC22A6 (0.53) | TTRALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL9816544 | 0.83 | SLC22A6 (0.44) | TTRSLC22A6MEN1KMT2AIDO1 | |
| SCHEMBL6695311 | 0.81 | SLC22A6 (0.41) | TTRALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL5690330 | 0.80 | ALDH1A1 (0.46) | TTRALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL30553876 | 0.80 | ALDH1A1 (0.46) | TTRALDH1A1TDP1CYP3A4TSHR | |
| Sulfuric Acid SCHEMBL8642510 | 0.80 | TTR (0.72) | TTRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL6812319 | 0.77 | ALDH1A1 (0.43) | TTRALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL6037265 | 0.77 | CA2 (0.50) | TDP1SLC22A6MEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669380-B1 | Process for the preparation of azo dyes | CIBA SC HOLDING AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| EP-0395587-B1 | Method for controlling and optimizing industrial processes for manufacturing dyes | CIBA GEIGY AG (CH) | 1997-03-12 | — | — | EP | disclosed |
| EP-0669380-A2 | Process for the preparation of azo dyes | CIBA-GEIGY AG (CH) | 1995-08-30 | — | — | EP | disclosed |
| EP-0395587-A2 | Method for controlling and optimizing industrial processes for manufacturing dyes | CIBA-GEIGY AG (CH) | 1990-10-31 | — | — | EP | disclosed |