Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755609 | 0.83 | TTR (0.55) | SLC22A6TTRAURKAAURKBMEN1 | |
| SCHEMBL10647420 | 0.82 | SLC22A6 (0.53) | SLC22A6TTRMEN1KMT2AESR1 | |
| SCHEMBL11124814 | 0.80 | IDO1 (0.53) | SLC22A6TTRAURKAAURKBMEN1 | |
| SCHEMBL29414155 | 0.80 | IDO1 (0.53) | SLC22A6TTRAURKAAURKBMEN1 | |
| SCHEMBL6695311 | 0.79 | SLC22A6 (0.41) | SLC22A6TTRAURKAAURKBMEN1 | |
| SCHEMBL11312662 | 0.78 | F10 (0.39) | SLC22A6MEN1KMT2AGAAKDM4E | |
| SCHEMBL8017323 | 0.77 | SLC22A6 (0.42) | SLC22A6TTRMEN1KMT2AGAA | |
| SCHEMBL5690330 | 0.75 | ALDH1A1 (0.46) | SLC22A6TTRGAAFABP1KDM4E | |
| SCHEMBL30553876 | 0.75 | ALDH1A1 (0.46) | SLC22A6TTRGAAFABP1KDM4E | |
| SCHEMBL3829786 | 0.74 | FABP1 (0.49) | SLC22A6MEN1KMT2AESR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174909-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0119441-B1 | REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0174909-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | disclosed |
| EP-0031099-B1 | COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |