SCHEMBL7756015

SCHEMBL7756015

CCN(CC)c1ccc(NC2(NC(=O)c3ccc(C)cc3)C(=O)N(c3ccccc3)N=C2c2cccc3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
NPC1 O15118 3/20 0.39
PLK1 P53350 1/20 0.37
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GHSR Q92847 4/20 0.36
HCRTR1 O43613 1/20 0.36
KDM1A O60341 1/20 0.36
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 1/20 0.35
KDR P35968 1/20 0.34
GBA1 P04062 1/20 0.34
NOX1 Q9Y5S8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760674 0.96 KMT2A (0.41) KMT2AMEN1NPC1PLK1MAPT
SCHEMBL7756065 0.90 MEN1 (0.42) KMT2AMEN1NPC1PLK1MAPT
SCHEMBL7756077 0.90 MEN1 (0.43) KMT2AMEN1NPC1PLK1MAPT
Diethylamine SCHEMBL7756020 0.88 L3MBTL1 (0.39) KMT2AMEN1NPC1MAPTL3MBTL1
SCHEMBL7759279 0.87 GHSR (0.40) KMT2AMEN1NPC1MAPTGHSR
SCHEMBL7762429 0.83 MEN1 (0.36) KMT2AMEN1NPC1PLK1MAPT
SCHEMBL7760668 0.83 CNR2 (0.41) KMT2AMEN1NPC1MAPTL3MBTL1
SCHEMBL8973266 0.82 MEN1 (0.39) KMT2AMEN1NPC1PLK1MAPT
SCHEMBL7756028 0.82 MEN1 (0.41) KMT2AMEN1NPC1PLK1MAPT
SCHEMBL7760648 0.82 CNR2 (0.43) KMT2AMEN1NPC1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed