Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754864 | 0.98 | LMNA (0.36) | LMNAALDH1A1CYP3A4GPR84SMPD1 | |
| SCHEMBL7755407 | 0.98 | LMNA (0.36) | LMNAALDH1A1CYP3A4GPR84SMPD1 | |
| SCHEMBL7752021 | 0.93 | ALDH1A1 (0.33) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL7755400 | 0.93 | ALDH1A1 (0.35) | LMNAALDH1A1CYP3A4CA2TSHR | |
| SCHEMBL9070541 | 0.93 | LMNA (0.44) | LMNAGPR84SMPD1CA12CA1 | |
| SCHEMBL7752041 | 0.92 | CYP3A4 (0.33) | LMNAALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL7756128 | 0.92 | CYP3A4 (0.33) | LMNAALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL8757628 | 0.92 | ALDH1A1 (0.34) | LMNAALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL7756115 | 0.92 | ALDH1A1 (0.34) | LMNAALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL9073883 | 0.92 | LMNA (0.42) | LMNAGPR84SMPD1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |