SCHEMBL7756259

Cc1cc2c(cc1C13CCC(=CCc4ccc(C(=O)OC(=O)c5ccc(CC=C6CCC7(c8ccc9c(c8)C(C)(C)CCC9(C)C)CC67)nc5)cn4)C1C3)C(C)(C)CCC2(C)C

nearest known ligand 0.37

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	RXRA	P19793	16/20	0.37

▸	RXRB	P28702	9/20	0.37

▸	RXRG	P48443	9/20	0.37

▸	RARA	P10276	4/20	0.37

▸	RARB	P10826	4/20	0.37

▸	RARG	P13631	3/20	0.37

▸	PPARG	P37231	2/20	0.37

▸	CYP3A4	P08684	2/20	0.34

▸	CYP26A1	O43174	4/20	0.33

▸	CYP26B1	Q9NR63	4/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7756272	0.96	RXRA (0.35)	RXRARXRBRXRGRARARARB
SCHEMBL7756256	0.92	RXRA (0.46)	RXRARXRBRXRGRARARARB
SCHEMBL7756251	0.92	RXRA (0.46)	RXRARXRBRXRGRARARARB
SCHEMBL7756267	0.89	RXRA (0.43)	RXRARXRBRXRGRARARARB
SCHEMBL7756261	0.89	RXRA (0.43)	RXRARXRBRXRGRARARARB
SCHEMBL7789372	0.86	RXRA (0.51)	RXRARXRBRXRGRARARARB
SCHEMBL7789369	0.86	RXRA (0.51)	RXRARXRBRXRGRARARARB
SCHEMBL7754580	0.86	RXRA (0.46)	RXRARXRBRXRGRARARARB
SCHEMBL7754583	0.86	RXRA (0.46)	RXRARXRBRXRGRARARARB
SCHEMBL7755025	0.84	RXRA (0.39)	RXRARXRBRXRGRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1077919-A1	NEW COMPOUNDS, THEIR PREPARATION AND USE	NOVO NORDISK A/S (DK)	2001-02-28	—	—	EP	disclosed
WO-1999058486-A1	NEW COMPOUNDS, THEIR PREPARATION AND USE	NOVO NORDISK A/S (DK)	1999-11-18	—	—	WO	disclosed