SCHEMBL7756261

CC1(C)CCC(C)(C)c2cc(C34CC/C(=C/Cc5ccc(C(=O)O)cc5)C3C4)ccc21.Cc1cc2c(cc1C13CC/C(=C/Cc4ccc(C(=O)O)cn4)C1C3)C(C)(C)CCC2(C)C

nearest known ligand 0.43

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	RXRA	P19793	17/20	0.43

▸	RXRB	P28702	9/20	0.43

▸	RXRG	P48443	8/20	0.43

▸	RARB	P10826	5/20	0.43

▸	RARG	P13631	5/20	0.43

▸	RARA	P10276	4/20	0.43

▸	PPARG	P37231	1/20	0.43

▸	CYP26A1	O43174	4/20	0.39

▸	CYP26B1	Q9NR63	3/20	0.39

▸	CYP3A4	P08684	2/20	0.37

▸	CRABP2	P29373	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7756267	1.00	RXRA (0.43)	RXRARXRBRXRGRARBRARG
SCHEMBL7756251	0.96	RXRA (0.46)	RXRARXRBRXRGRARBRARG
SCHEMBL7756256	0.96	RXRA (0.46)	RXRARXRBRXRGRARBRARG
SCHEMBL7756272	0.91	RXRA (0.35)	RXRARXRBRXRGRARBRARG
SCHEMBL7789372	0.91	RXRA (0.51)	RXRARXRBRXRGRARBRARG
SCHEMBL7789369	0.91	RXRA (0.51)	RXRARXRBRXRGRARBRARG
SCHEMBL7754583	0.91	RXRA (0.46)	RXRARXRBRXRGRARBRARG
SCHEMBL7754580	0.91	RXRA (0.46)	RXRARXRBRXRGRARBRARG
SCHEMBL7756259	0.89	RXRA (0.37)	RXRARXRBRXRGRARBRARG
SCHEMBL7757722	0.86	RXRA (0.51)	RXRARXRBRXRGRARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1077919-A1	NEW COMPOUNDS, THEIR PREPARATION AND USE	NOVO NORDISK A/S (DK)	2001-02-28	—	—	EP	claimed
WO-1999058486-A1	NEW COMPOUNDS, THEIR PREPARATION AND USE	NOVO NORDISK A/S (DK)	1999-11-18	—	—	WO	claimed