Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030411 | 0.88 | SCN9A (0.43) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7027183 | 0.86 | POLB (0.51) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8741772 | 0.85 | TP53 (0.47) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8330737 | 0.82 | MEN1 (0.40) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8686158 | 0.81 | MAPT (0.40) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7756511 | 0.78 | KDM4E (0.48) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7020881 | 0.77 | MAPT (0.51) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8741771 | 0.76 | DYRK3 (0.48) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6584881 | 0.76 | KDM4E (0.56) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7028491 | 0.76 | DHODH (0.48) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755457-B1 | Novel Aryl-N-Alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection | LUMIGEN INC (US) | 2001-02-21 | — | — | EP | disclosed |
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |