Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030411 | 0.85 | SCN9A (0.43) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7756508 | 0.82 | KMT2A (0.46) | MEN1KMT2ANPC1DYRK1AABCG2 | |
| SCHEMBL8686158 | 0.80 | MAPT (0.40) | MEN1KMT2ANPC1ABCG2POLB | |
| SCHEMBL7027183 | 0.79 | POLB (0.51) | MEN1KMT2ANPC1POLBMAPT | |
| SCHEMBL8333201 | 0.76 | POLB (0.52) | NPC1CDK9DYRK1APOLBMAPT | |
| SCHEMBL7756511 | 0.74 | KDM4E (0.48) | MEN1KMT2ANPC1ABCG2POLB | |
| SCHEMBL8333267 | 0.71 | RAB9A (0.41) | MEN1KMT2ANPC1CDK9DYRK1A | |
| SCHEMBL7797045 | 0.71 | MAPT (0.48) | MEN1KMT2ANPC1POLBMAPT | |
| SCHEMBL6931307 | 0.71 | MAPT (0.43) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL7757071 | 0.70 | ESR1 (0.41) | MEN1KMT2AABCG2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778946-A4 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 1999-01-27 | — | — | EP | disclosed |
| CN-1161083-A | Novel method and kits for producing light from 9,10-azetine compound | LUMIGEN INC (US) | 1997-10-01 | — | — | CN | disclosed |
| EP-0778946-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996007912-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1996-03-14 | — | — | WO | disclosed |