Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7531424 | 0.98 | KDM4E (0.54) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL22969068 | 0.94 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3036200 | 0.91 | KDM4E (0.56) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7536012 | 0.88 | KMT2A (0.56) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7020881 | 0.86 | MAPT (0.51) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7533914 | 0.84 | CYP2D6 (0.55) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL17060420 | 0.83 | KDM4E (0.61) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL22969064 | 0.82 | MAPT (0.49) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL641481 | 0.82 | KDM4E (0.62) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7702486 | 0.82 | ALOX15 (0.57) | KDM4EMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6635437-B2 | Useful in methods for producing light and in assays for phosphatase enzymes and enzyme inhibitors and in assays employing enzyme-labeled specific binding pairs | LUMIGEN, INC. | 2003-10-21 | — | — | US | disclosed |
| EP-0819119-B1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-20030023089-A1 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes | AKHAVAN-TAFTI HASHEM (US) | 2003-01-30 | — | — | US | disclosed |
| US-5750698-A | USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE | LUMIGEN, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5686258-A | Chemiluminescent detection of hydrolytic enzymes using an acridan | LUMIGEN, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |
| EP-0778947-A1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN, INC. (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0750748-A4 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5593845-A | BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0750748-A1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-02 | — | — | EP | disclosed |
| WO-1996007911-A1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN, INC. (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1995023971-A1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030023089-A1 | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes | PPP6C, PPP4C, PPP2CA | KDM4E 3418/4885MEN1 4650/4885KMT2A 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.