Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030411 | 0.81 | SCN9A (0.43) | MAPTALDH1A1PKMMEN1KMT2A | |
| SCHEMBL7756508 | 0.81 | KMT2A (0.46) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL8330737 | 0.80 | MEN1 (0.40) | MAPTALDH1A1POLBNPC1TOP2A | |
| SCHEMBL7027183 | 0.76 | POLB (0.51) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL6931307 | 0.73 | MAPT (0.43) | MAPTALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL8333201 | 0.73 | POLB (0.52) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL8686420 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL7756511 | 0.71 | KDM4E (0.48) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL6930359 | 0.68 | MAOA (0.43) | MAPTALDH1A1POLBNPC1NQO2 | |
| SCHEMBL7757071 | 0.67 | ESR1 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723295-A | MULTISTAGE CHEMILUMINESCENT ASSAY WITH PEROXIDASE ENZYME, PH ADJUSTMENT | LUMIGEN, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5670644-A | CHEMILUMINESCENT REACTIONS, PEROXIDASE AND PH FOR IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-09-23 | — | — | US | disclosed |