Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.69 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.49 |
| ▸ | RXRB | P28702 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | RARG | P13631 | 5/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761224 | 0.82 | RXRA (0.54) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL30012842 | 0.82 | RXRA (1.00) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL3453249 | 0.82 | RXRA (1.00) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7760195 | 0.82 | RXRA (0.77) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7756598 | 0.79 | RXRA (0.64) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7756527 | 0.78 | RXRA (0.49) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7762990 | 0.77 | RXRA (0.68) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7759877 | 0.77 | CYP26B1 (0.64) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7759879 | 0.77 | CYP26B1 (0.64) | RXRACYP26B1CYP26A1RXRBCYP3A4 | |
| SCHEMBL7756603 | 0.77 | RXRA (0.57) | RXRACYP26B1CYP26A1RXRBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | claimed |
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | disclosed |
| EP-0915823-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998022423-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-05-28 | — | — | WO | disclosed |