Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948181 | 0.87 | SIGMAR1 (0.51) | HTR1AHTR2CSIGMAR1CHRM2TP53 | |
| SCHEMBL8948196 | 0.87 | SIGMAR1 (0.61) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948338 | 0.83 | HTR1A (0.54) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948102 | 0.82 | SIGMAR1 (0.63) | POLBHTR1AHTR2CSIGMAR1 | |
| SCHEMBL8948245 | 0.79 | SIGMAR1 (0.52) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL7761677 | 0.77 | PDE3B (0.56) | POLBHTR1AHTR2CCHRM2 | |
| SCHEMBL8109676 | 0.76 | SIGMAR1 (0.59) | HTR1AHTR2CSIGMAR1 | |
| SCHEMBL27318311 | 0.76 | SIGMAR1 (0.48) | POLBHTR1AHTR2CSIGMAR1 | |
| SCHEMBL9685601 | 0.75 | SIGMAR1 (0.60) | HTR1AHTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8871359 | 0.75 | SIGMAR1 (0.58) | HTR1AHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |