Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948181 | 0.85 | SIGMAR1 (0.51) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8948196 | 0.85 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7756738 | 0.82 | POLB (0.54) | SIGMAR1HTR1AHTR2CPOLB | |
| SCHEMBL8948338 | 0.81 | HTR1A (0.54) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8948245 | 0.79 | SIGMAR1 (0.52) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9618249 | 0.78 | CYP1A2 (0.61) | SIGMAR1POLB | |
| SCHEMBL7760487 | 0.77 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8109676 | 0.76 | SIGMAR1 (0.59) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7761668 | 0.76 | MARS1 (0.48) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437749 | 0.76 | SIGMAR1 (0.63) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |