Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 1.00 |
| ▸ | HTR1A | P08908 | 5/20 | 0.63 |
| ▸ | HTR2C | P28335 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759816 | 0.87 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2CACHE | |
| SCHEMBL7756716 | 0.84 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2CACHE | |
| SCHEMBL7759846 | 0.80 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2CACHE | |
| SCHEMBL9449586 | 0.79 | SIGMAR1 (0.69) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7762759 | 0.79 | HTR1A (0.65) | SIGMAR1HTR1AHTR2CACHE | |
| SCHEMBL9232854 | 0.77 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9449797 | 0.76 | HTR1A (0.72) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8948102 | 0.76 | SIGMAR1 (0.63) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759827 | 0.75 | SIGMAR1 (0.67) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8948162 | 0.75 | SIGMAR1 (0.69) | SIGMAR1HTR1AHTR2CTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | claimed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |