Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734271 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1LMNAPTGS2 | |
| Hydrochloric Acid SCHEMBL7753276 | 0.98 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1LMNAPTGS2 | |
| Hydrochloric Acid SCHEMBL6741437 | 0.98 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1LMNAPTGS2 | |
| SCHEMBL12898741 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1LMNAPTGS2 | |
| SCHEMBL6738103 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTPTGS1MMEACE | |
| Hydrochloric Acid SCHEMBL6739306 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTPTGS1MMEACE | |
| SCHEMBL12908822 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1KMT2A | |
| SCHEMBL18629893 | 0.77 | PTGS1 (0.47) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL14755648 | 0.76 | PTGS1 (0.45) | ALDH1A1MAPTPTGS1 | |
| Dl-Penicillamine SCHEMBL5237609 | 0.76 | ALDH1A1 (0.67) | ALDH1A1MAPTPTGS1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001058928-A1 | N-TERMINAL D(-)-PENICILLAMINE PEPTIDES AS ALDEHYDE SEQUESTRATION AGENTS | NAGASAWA HERBERT T (US) | 2001-08-16 | — | — | WO | disclosed |