Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6739306 | 0.98 | ALDH1A1 (0.47) | ALDH1A1MAPTPTGS1ECE1ACE | |
| SCHEMBL6734271 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1ECE1ACE | |
| SCHEMBL18629893 | 0.81 | PTGS1 (0.47) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL7756796 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1ECE1ACE | |
| Hydrochloric Acid SCHEMBL7753276 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1ECE1ACE | |
| Hydrochloric Acid SCHEMBL6741437 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1ECE1ACE | |
| SCHEMBL14755648 | 0.80 | PTGS1 (0.45) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL14752342 | 0.79 | ANPEP (0.51) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL12908822 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL9330023 | 0.75 | ADRA1A (0.43) | PTGS1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686336-B2 | ALCOHOLISM THERAPY | FEDERAL GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRES | 2004-02-03 | — | — | US | claimed |
| US-6686336-B2 | ALCOHOLISM THERAPY | FEDERAL GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRES | 2004-02-03 | — | — | US | disclosed |
| US-20010041789-A1 | N-terminal D(-)-penicillamine peptides as aldehyde sequestration agents | FEDERAL GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2001-11-15 | — | — | US | disclosed |
| WO-2001058928-A1 | N-TERMINAL D(-)-PENICILLAMINE PEPTIDES AS ALDEHYDE SEQUESTRATION AGENTS | NAGASAWA HERBERT T (US) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041789-A1 | N-terminal D(-)-penicillamine peptides as aldehyde sequestration agents | ADH1C, ADH1A, ADH5 | ALDH1A1 4/4885MAPT 2369/4885PTGS1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.