Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756827 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTT | |
| SCHEMBL7756835 | 0.74 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL7755223 | 0.70 | CA1 (0.34) | ALDH1A1 | |
| SCHEMBL7756826 | 0.69 | CA1 (0.35) | ALDH1A1 | |
| SCHEMBL9099317 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL8778811 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL8778823 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL9101224 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL9102994 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT | |
| SCHEMBL3683856 | 0.68 | KEAP1 (0.59) | KEAP1NFE2L2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792255-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0792255-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015092-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |
| US-5482650-A | Liquid crystal compounds having perfluoroether terminal portions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |