Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756511 | 0.85 | KDM4E (0.48) | ABCG2RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7030411 | 0.84 | SCN9A (0.43) | ACP1SMN1; SMN2HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL6931307 | 0.81 | MAPT (0.43) | RAB9ASMN1; SMN2HPGDL3MBTL1MAOB | |
| SCHEMBL7027183 | 0.81 | POLB (0.51) | TNKSTNKS2RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28022528 | 0.79 | ESR1 (0.39) | ESR1ACP1TNKSWNT3ATNKS2 | |
| SCHEMBL7755739 | 0.78 | ACHE (0.38) | KIF11SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7755153 | 0.77 | CA12 (0.37) | RAB9AMEN1KMT2AGAAMAPT | |
| SCHEMBL7027469 | 0.75 | ELANE (0.39) | RAB9ASMN1; SMN2HPGDMAOBALDH1A1 | |
| SCHEMBL7756508 | 0.74 | KMT2A (0.46) | ACP1ABCG2RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23731489 | 0.73 | ALDH1A1 (0.45) | RAB9AKIF11SMN1; SMN2MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755457-B1 | Novel Aryl-N-Alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection | LUMIGEN INC (US) | 2001-02-21 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |