Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | SHBG | P04278 | 4/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832271 | 0.83 | CYP19A1 (0.63) | CYP19A1SHBGSERPINA6ALDH1A1OR51E2 | |
| SCHEMBL8083229 | 0.83 | CYP19A1 (0.63) | CYP19A1SHBGSERPINA6ALDH1A1OR51E2 | |
| SCHEMBL11208177 | 0.75 | CYP19A1 (0.47) | CYP19A1SHBGSERPINA6ALDH1A1OR51E2 | |
| SCHEMBL11208172 | 0.75 | CYP19A1 (0.47) | CYP19A1SHBGSERPINA6ALDH1A1OR51E2 | |
| SCHEMBL11208173 | 0.75 | CYP19A1 (0.47) | CYP19A1SHBGSERPINA6ALDH1A1OR51E2 | |
| SCHEMBL3816340 | 0.75 | SHBG (0.68) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11647165 | 0.75 | SHBG (0.68) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL4013302 | 0.75 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11515579 | 0.75 | SHBG (0.68) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL15515737 | 0.74 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090029-A1 | 14,15-CYCLOPROPANOSTEROIDS OF THE 19-NORANDROSTANE SERIES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Jenapharm GmbH & Co. KG (DE) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067276-A1 | 14,15-CYCLOPROPANOSTEROIDS OF THE 19-NORANDROSTANE SERIES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | JENAPHARM GMBH & CO. KG (DE) | 1999-12-29 | — | — | WO | disclosed |