SCHEMBL7757148

SCHEMBL7757148

CCOC(=O)NOCc1cc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPOX P50336 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756617 0.80
SCHEMBL27425565 0.79 BAZ2B (0.32) PPOX
SCHEMBL7757157 0.79 PPOX (0.34) PPOX
SCHEMBL27559545 0.76 GAA (0.35) KDM4EALDH1A1HPGD
SCHEMBL10574869 0.75 L3MBTL1 (0.30) PPOX
SCHEMBL10574871 0.75
SCHEMBL26027275 0.74 GAA (0.39) HPGD
SCHEMBL7833799 0.74 KMT2A (0.38) KDM4EALDH1A1HPGD
SCHEMBL7019278 0.74 BCAT2 (0.30)
SCHEMBL27559423 0.73 NOTUM (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0836594-B1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AG (DE) 2001-03-07 EP disclosed
US-6057269-A HERBICIDES AND FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2000-05-02 US disclosed
CN-1192737-A Benzylhydroxylamines and intermediates used to prepare them BASF AG (DE) 1998-09-09 CN disclosed
EP-0836594-A1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AKTIENGESELLSCHAFT (DE) 1998-04-22 EP disclosed
WO-1997002253-A1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed