Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82662 | 0.83 | CYP3A4 (0.66) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL730130 | 0.79 | ALDH1A1 (0.48) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL8591266 | 0.79 | CYP3A4 (0.60) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL5836751 | 0.78 | — | — | |
| SCHEMBL10352313 | 0.78 | — | — | |
| SCHEMBL2779972 | 0.78 | — | — | |
| SCHEMBL4439269 | 0.77 | TSHR (0.44) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL4439273 | 0.77 | TSHR (0.44) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL27305 | 0.77 | ALDH1A1 (0.50) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL2887233 | 0.76 | TSHR (0.48) | TSHRCYP3A4ATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092010-A1 | DIHYDRO-2H-ISOINDOLE ESTER COMPOUND | SHANGHAI MAIUS PHARMACEUTICAL CO. LTD. (CN) | 2025-03-20 | — | — | US | disclosed |
| EP-4486747-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-118900839-A | Antiviral compounds and methods of making and using the same | 吉利德科学公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115677718-B | Methyl methylamine derivative preparation, pharmaceutical composition and application thereof | 武汉思瓴生物科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4385983-A1 | DIHYDRO-2H-ISOINDOLE ESTER COMPOUND | Shanghai Maius Pharmaceutical Co. Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| WO-2024094637-A1 | PROCESS FOR THE PREPARATION OF CYCLIC KETONES | ARXADA AG (CH) | 2024-05-10 | — | — | WO | disclosed |
| US-20230382940-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2023-11-30 | — | — | US | disclosed |
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| CN-115677718-A | Methylmethylamine derivative preparation, pharmaceutical composition and application thereof | 武汉思瓴生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113861027-A | Method for continuous flow synthesis of chloroformate compound | 爱斯特（成都）生物制药股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-0850927-B1 | Novel oxalic acid peroxide compositions and their uses | ATOFINA CHEM INC (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5866712-A | POLYMERIZATION AND CURING CATALYSTS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0850927-A1 | Novel oxalic acid peroxide compositions and uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5451654-A | Addition polymerization catalyst | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5387654-A | Hydroxy-peroxides and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0381135-B1 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5304649-A | Curing agent for unsaturated polyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| US-5304650-A | Reacting chloroformates with amino alcohol derivatives in aqueous alkali metal hydroxide solution | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |
| EP-0381135-A2 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA, INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4017505-A | FUNGICIDES, ANTHELMINTICS | MERCK & CO., INC. (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382940-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | EIF2AK2, MAVS, ZC3HAV1 | TSHR 4609/4885CYP3A4 1546/4885ATM 3806/4885 |
| US-20250092010-A1 | DIHYDRO-2H-ISOINDOLE ESTER COMPOUND | CYP3A5, CYP2D6, CYP3A7 | TSHR 4691/4885CYP3A4 4/4885ATM 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.