Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 6/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593135 | 0.85 | FDPS (0.36) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL9800162 | 0.78 | SMPD1 (0.36) | EPHX1CES2FDPSGGPS1SMPD1 | |
| SCHEMBL3984851 | 0.72 | EPHX1 (0.37) | EPHX1CES2FDPSGGPS1SMPD1 | |
| SCHEMBL8756198 | 0.69 | SMPD1 (0.42) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL6843560 | 0.67 | SMPD1 (0.45) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL8756203 | 0.67 | SMPD1 (0.45) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL8755460 | 0.67 | SMPD1 (0.45) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL8755496 | 0.67 | SMPD1 (0.45) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL6841738 | 0.67 | SMPD1 (0.45) | CES2FDPSGGPS1SMPD1 | |
| SCHEMBL8472572 | 0.66 | TSHR (0.44) | CES2FDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092714-A2 | Process for the synthesis of benzo[b]thiophenes | Eli Lilly & Company (US) | 2001-04-18 | — | — | EP | disclosed |
| US-5606075-A | CYCLIZATION IN THE PRESENCE OF AN ACID CATALYST | ELI LILLY AND COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5512701-A | REACTING SULFOXIDE DERIVATIVE WITH A SILYATING AGENT TO FORM SULFENATE SILYL ESTER, OPTIONALLY REACTING INTERMEDIATE WITH AN AMINE AND/OR A MERCAPTAN | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |