Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757329 | 0.78 | EPHX1 (0.38) | SMPD1EPHX1CES2GGPS1FDPS | |
| SCHEMBL8593135 | 0.75 | FDPS (0.36) | SMPD1MAPTMEN1KMT2AATM | |
| SCHEMBL7185920 | 0.73 | TSHR (0.43) | SMPD1MAPTMEN1KMT2AATM | |
| SCHEMBL7590099 | 0.73 | SMPD1 (0.33) | SMPD1MAPTMEN1KMT2AATM | |
| SCHEMBL7185274 | 0.73 | TSHR (0.49) | SMPD1MAPTMEN1KMT2AATM | |
| SCHEMBL7180580 | 0.71 | TSHR (0.44) | SMPD1ATMCES2CYP3A4TSHR | |
| SCHEMBL7185236 | 0.71 | TSHR (0.46) | SMPD1MAPTMEN1KMT2AATM | |
| SCHEMBL3984851 | 0.68 | EPHX1 (0.37) | SMPD1EPHX1CES2GGPS1TSHR | |
| SCHEMBL5376060 | 0.68 | SMPD1 (0.38) | SMPD1CES2GGPS1TSHRFDPS | |
| SCHEMBL6892063 | 0.68 | SMPD1 (0.38) | SMPD1MAPTMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021600-A | New silylating agent for the preparation of chromatographic supports | ENIRICERCHE S.P.A. (IT) | 1991-06-04 | — | — | US | claimed |
| EP-0357137-A2 | New silylating agent for the preparation of chromatographic supports | ENIRICERCHE S.p.A. (IT) | 1990-03-07 | — | — | EP | claimed |
| JP-2131489-A | — | — | None | — | — | JP | disclosed |
| US-5021600-A | New silylating agent for the preparation of chromatographic supports | ENIRICERCHE S.P.A. (IT) | 1991-06-04 | — | — | US | disclosed |
| JP-H02131489-A | SILYLATING AGENT | ENIRICERCHE SPA | 1990-05-21 | — | — | JP | disclosed |
| EP-0357137-A2 | New silylating agent for the preparation of chromatographic supports | ENIRICERCHE S.p.A. (IT) | 1990-03-07 | — | — | EP | disclosed |