Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757363 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL7757799 | 0.72 | CHRNB2 (0.59) | MEN1KMT2ACHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL7759630 | 0.71 | CHRNB2 (0.58) | MEN1KMT2ACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL9394256 | 0.67 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL229329 | 0.67 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL229328 | 0.67 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL31560044 | 0.67 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL7756342 | 0.63 | CHRNA3 (0.71) | MEN1KMT2ACHRNB2CHRNA3CHRNA4 | |
| Methyl Alcohol SCHEMBL28478479 | 0.63 | NPC1 (0.89) | MEN1KMT2ANPC1RAB9AATM | |
| Hydrochloric Acid SCHEMBL7753623 | 0.62 | CHRNA3 (0.69) | MEN1KMT2ACHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049690-A1 | 9-AZABICYCLO[4.2.1]NON-2-ENE DERIVATIVES AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS | UNIVERSITY OF BRISTOL (GB) | 2001-07-12 | — | — | WO | disclosed |