SCHEMBL7757545

SCHEMBL7757545

O=C(NCl)Nc1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
TAAR1 Q96RJ0 1/20 0.60
ALDH1A1 P00352 1/20 0.57
RAB9A P51151 10/20 0.56
NPC1 O15118 7/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
HTT P42858 3/20 0.56
MAPT P10636 2/20 0.56
MAPK1 P28482 2/20 0.56
XBP1 P17861 1/20 0.56
POLB P06746 2/20 0.55
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CA4 P22748 1/20 0.55
CA7 P43166 1/20 0.55
TGM2 P21980 1/20 0.52
EPHX1 P07099 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3070329 0.86 KMT2A (0.76) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL17119070 0.81 RAB9A (0.70) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL1885507 0.80 ALDH1A1 (0.67) KMT2AMEN1ALDH1A1RAB9ANPC1
SCHEMBL14279805 0.79 KMT2A (0.56) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL3183978 0.78 TDP1 (0.59) KMT2AMEN1ALDH1A1RAB9ANPC1
SCHEMBL11056635 0.78 SMN1; SMN2 (0.74) KMT2AMEN1TAAR1RAB9ANPC1
SCHEMBL7951644 0.78 ALDH1A1 (0.64) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL8665625 0.78 ALDH1A1 (0.63) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL8423118 0.78 MEN1 (0.60) KMT2AMEN1TAAR1ALDH1A1RAB9A
SCHEMBL18031165 0.78 MAOA (0.67) KMT2AMEN1TAAR1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885TAAR1 4098/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885MEN1 980/4885TAAR1 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.