Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13787409 | 0.80 | RAF1 (0.43) | GAAMEN1KMT2ARAF1DAO | |
| SCHEMBL1694410 | 0.77 | DAO (0.52) | GAAMEN1KMT2ARAF1DAO | |
| SCHEMBL28196751 | 0.76 | RAF1 (0.46) | GAAMEN1KMT2AHSD17B10RAF1 | |
| SCHEMBL11471040 | 0.76 | HSD17B10 (0.48) | GAAMEN1KMT2AHSD17B10RAF1 | |
| SCHEMBL28298682 | 0.74 | ALDH1A1 (0.56) | GAAMEN1KMT2AHSD17B10MAPT | |
| SCHEMBL7757560 | 0.74 | DAO (0.44) | GAAMEN1KMT2ARAF1HDAC3 | |
| SCHEMBL28196781 | 0.74 | RAF1 (0.45) | GAAMEN1KMT2AHSD17B10RAF1 | |
| SCHEMBL28873510 | 0.73 | RAB9A (0.55) | GAAMEN1KMT2AHSD17B10RAF1 | |
| SCHEMBL28855342 | 0.72 | RAF1 (0.49) | GAAMEN1KMT2AHSD17B10RAF1 | |
| SCHEMBL11692597 | 0.72 | ALDH1A1 (0.45) | GAAMEN1KMT2AHSD17B10RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107646035-A | Heterocyclyl methyl thieno uracil as adenosine A 2B receptor antagonists | 拜耳制药股份公司 | 2018-01-30 | — | — | CN | disclosed |