Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150206 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDLMNAALDH1A1 | |
| SCHEMBL8723281 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDLMNAALDH1A1 | |
| SCHEMBL12846719 | 0.91 | TDP1 (0.75) | TDP1ABCB1PGDLMNAALDH1A1 | |
| SCHEMBL16627355 | 0.86 | TDP1 (0.75) | TDP1PRKCAABCB1PGDLMNA | |
| SCHEMBL813363 | 0.86 | TDP1 (0.75) | TDP1PRKCAABCB1PGDLMNA | |
| SCHEMBL16312958 | 0.86 | TDP1 (0.81) | TDP1PRKCAABCB1PGDLMNA | |
| SCHEMBL9426447 | 0.84 | TDP1 (0.67) | TDP1ABCB1PGDLMNAALDH1A1 | |
| SCHEMBL8447422 | 0.84 | TDP1 (0.67) | TDP1ABCB1PGDLMNAALDH1A1 | |
| SCHEMBL3832133 | 0.83 | TDP1 (0.55) | TDP1PRKCAABCB1PGDLMNA | |
| SCHEMBL7218077 | 0.83 | TDP1 (0.64) | TDP1ABCB1PGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639586-B1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| US-5608045-A | DISODIUM SALT BY POT REACTING RHAMNOSE TRIACETATE WITH PHENYL DICHLOROPHOSPHATE IN PRESENCE OF TRIETHYLAMINE AND WITH /S/LEU-/S/TRP-OET IN SOLVENT, SAPONIFYING SEPARATED PRODUCT WITH ETHANOLIC BASE IN COLD, EVAPORATING ETHANOL | ADIR ET COMPAGNIE (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5591728-A | ENZYME INHIBITORS WITH AMIDE AND ESTER GROUPS | ADIR ET COMPAGNIE (FR) | 1997-01-07 | — | — | US | disclosed |
| US-5481030-A | USED AS AN ENDOTHELIN CONVERTASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0639586-A1 | Phosphonic acid derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-02-22 | — | — | EP | disclosed |