SCHEMBL9426447

SCHEMBL9426447

CC(=O)OCC(OC(C)=O)C(COCC(OC(C)=O)C(COC(C)=O)OC(C)=O)OC(C)=O

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.67
TSHR P16473 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PGD P52209 1/20 0.39
ABCB1 P08183 1/20 0.38
POLB P06746 1/20 0.38
MAPK1 P28482 1/20 0.38
TRPV1 Q8NER1 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
GAA P10253 1/20 0.33
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150206 0.93 TDP1 (0.75) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL8723281 0.93 TDP1 (0.75) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL12846719 0.93 TDP1 (0.75) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL9005157 0.90 TDP1 (0.60) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL11983607 0.88 TDP1 (0.58) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL8447422 0.86 TDP1 (0.67) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL7218077 0.84 TDP1 (0.64) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL16546894 0.84 TDP1 (0.64) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL7757654 0.84 TDP1 (0.64) TDP1TSHRALDH1A1LMNAHSD17B10
SCHEMBL11846043 0.83 TDP1 (0.62) TDP1TSHRALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336770-A Transglycosilation process for producing acyclic nucleosides AJINOMOTO CO., INC. (JP) 1994-08-09 US claimed
EP-0532878-A2 Process for producing acyclic nucleosides Ajinomoto Co., Inc. (JP) 1993-03-24 EP claimed
JP-5078329-A None JP disclosed
US-5336770-A Transglycosilation process for producing acyclic nucleosides AJINOMOTO CO., INC. (JP) 1994-08-09 US disclosed
JP-H0578329-A PRODUCTION OF NONCYCLIC NUCLEOTIDES AJINOMOTO CO INC 1993-03-30 JP disclosed
EP-0532878-A2 Process for producing acyclic nucleosides Ajinomoto Co., Inc. (JP) 1993-03-24 EP disclosed