Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 6/20 | 0.36 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 19/20 | 0.36 |
| ▸ | RXRB | P28702 | 9/20 | 0.35 |
| ▸ | RXRG | P48443 | 7/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751874 | 0.88 | RXRA (0.46) | RARGRARBRARARXRARXRB | |
| SCHEMBL7751877 | 0.84 | CYP3A4 (0.38) | RARGRARBRARARXRARXRB | |
| SCHEMBL7757685 | 0.81 | RXRA (0.52) | RARGRARBRARARXRARXRB | |
| SCHEMBL7790860 | 0.80 | RXRA (0.52) | RARGRARBRARARXRARXRB | |
| SCHEMBL7757702 | 0.74 | RXRA (0.45) | RARGRARBRARARXRARXRB | |
| SCHEMBL7786489 | 0.72 | RXRA (0.56) | RARGRARBRARARXRARXRB | |
| SCHEMBL7754577 | 0.70 | RXRA (0.49) | RARGRARBRARARXRARXRB | |
| SCHEMBL7751761 | 0.67 | RARB (0.38) | RARGRARBRARARXRARXRB | |
| SCHEMBL7757942 | 0.65 | RXRA (0.36) | RARGRARBRARARXRARXRB | |
| SCHEMBL7781814 | 0.65 | RARB (0.43) | RARGRARBRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |