Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460708 | 0.89 | KDM4E (0.40) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL28939537 | 0.84 | KDM4E (0.60) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL7755712 | 0.84 | MEN1 (0.42) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL9620834 | 0.84 | ACHE (0.49) | — | |
| SCHEMBL38662922 | 0.82 | ACHE (0.45) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL23461083 | 0.82 | ACHE (0.45) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10334858 | 0.80 | ACHE (0.48) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL9620764 | 0.79 | ACHE (0.51) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL346335 | 0.79 | PIN1 (0.41) | — | |
| SCHEMBL19900206 | 0.78 | SRD5A1 (0.42) | KDM4EALDH1A1MAPTHSD17B10SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |