Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378142 | 0.86 | KDM4E (0.61) | ACHEKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9620834 | 0.86 | ACHE (0.49) | ACHE | |
| SCHEMBL9621088 | 0.83 | NPC1 (0.43) | ACHE | |
| SCHEMBL7757705 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL346335 | 0.79 | PIN1 (0.41) | — | |
| SCHEMBL7755712 | 0.78 | MEN1 (0.42) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9620999 | 0.76 | ACHE (0.42) | ACHEKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6379762 | 0.76 | KDM4E (0.78) | ACHEKDM4EALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7448476 | 0.75 | ACHE (0.56) | ACHE | |
| SCHEMBL23460708 | 0.75 | KDM4E (0.40) | KDM4EALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |