Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589991 | 0.88 | MAPT (0.57) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL7759657 | 0.87 | ATM (0.55) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL7758173 | 0.86 | ATM (0.60) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL10542242 | 0.85 | GAA (0.54) | MAPTALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL7176512 | 0.85 | ATM (0.62) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL10915714 | 0.83 | ATM (0.62) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL1171418 | 0.82 | LMNA (0.56) | ATMMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7761464 | 0.81 | KMT2A (0.60) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL7761543 | 0.80 | LMNA (0.47) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL4073528 | 0.79 | TPSAB1 (0.53) | MAPTALDH1A1LMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062242-A1 | PRODRUGS OF SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |