Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758133 | 0.87 | KDM1A (0.59) | KMT2ARAB9AGAAKDM1ARCOR1 | |
| SCHEMBL7758912 | 0.86 | KDM1A (0.64) | KMT2ARAB9AGAAKDM1ARCOR1 | |
| SCHEMBL7315510 | 0.85 | KDM1A (0.67) | KMT2ARAB9AGAAKDM1ARCOR1 | |
| SCHEMBL7624965 | 0.83 | KDM1A (0.67) | KMT2ARAB9AGAAKDM1ARCOR1 | |
| SCHEMBL11925397 | 0.81 | KDM1A (0.64) | KMT2ARAB9AGAAKDM1ARCOR1 | |
| SCHEMBL7758148 | 0.81 | ATM (0.54) | KMT2ARAB9AGAAMEN1LMNA | |
| SCHEMBL7485457 | 0.81 | KMT2A (0.75) | KMT2ARAB9AGAAMEN1NPC1 | |
| SCHEMBL7761543 | 0.80 | LMNA (0.47) | KMT2ARAB9AGAANPC1LMNA | |
| SCHEMBL10916834 | 0.79 | KMT2A (0.76) | KMT2ARAB9AGAAMEN1NPC1 | |
| SCHEMBL9635671 | 0.79 | POLB (0.74) | KDM1ARCOR1LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062242-A1 | PRODRUGS OF SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |