SCHEMBL7758189

SCHEMBL7758189

CCCCOc1cc2c(cc1OCCCC)C(=N)N=C2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
TLR8 Q9NR97 3/20 0.34
CYP19A1 P11511 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CNR2 P34972 1/20 0.32
CDC7 O00311 1/20 0.32
ROCK2 O75116 1/20 0.32
MAP4K4 O95819 1/20 0.32
PIM1 P11309 1/20 0.32
PRKACA P17612 1/20 0.32
CDK2 P24941 1/20 0.32
GSK3B P49841 1/20 0.32
HIPK2 Q9H2X6 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.32
NPC1 O15118 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754881 0.85 ACHE (0.35) CYP3A4
SCHEMBL7756217 0.79 CYP2D6 (0.42) CYP1A2CYP2C9CYP2C19CYP19A1CYP3A4
SCHEMBL7752176 0.72 CYP1A2 (0.43) CYP1A2CYP2C9CYP2C19TLR8CYP19A1
SCHEMBL5154676 0.71 ALDH1A1 (0.45) CYP1A2CYP2C9CYP2C19TLR8CYP19A1
SCHEMBL13412631 0.70 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19TLR8CYP3A4
SCHEMBL7755326 0.66 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19TLR8CYP3A4
SCHEMBL30485171 0.66 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19TLR8CYP3A4
SCHEMBL30485172 0.66 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19TLR8CYP3A4
SCHEMBL347849 0.64 TLR8 (0.45) CYP1A2CYP2C9CYP2C19TLR8CYP19A1
SCHEMBL7739532 0.63 CYP1A2 (0.45) CYP1A2CYP2C9CYP2C19TLR8NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1073407-A1 HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE ORQUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES L'OREAL (FR) 2001-02-07 EP disclosed
EP-1056435-A1 DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES L'OREAL (FR) 2000-12-06 EP disclosed
WO-2000038640-A1 HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES L'OREAL (FR) 2000-07-06 WO disclosed
WO-2000038641-A1 DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES L'OREAL (FR) 2000-07-06 WO disclosed