Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087044 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6087042 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7037489 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7753948 | 0.81 | NOX4 (0.35) | SMN1; SMN2ALDH1A1HPGDDRD1ADORA3 | |
| SCHEMBL6087276 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2466620 | 0.80 | GRIN1 (0.43) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6086864 | 0.80 | HPGD (0.44) | KDM4EALDH1A1HPGDHSD17B10ADORA3 | |
| SCHEMBL7758804 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7759888 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7756725 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |