Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484944 | 0.86 | PDE3B (0.31) | — | |
| SCHEMBL7753948 | 0.84 | NOX4 (0.35) | NOX4DAOHPGDGRIN1ALDH1A1 | |
| SCHEMBL6086817 | 0.83 | HPGD (0.43) | HPGDALDH1A1KDM4ETLR7 | |
| SCHEMBL7756623 | 0.80 | DAO (0.36) | NOX4DAOHPGDGRIN1ALDH1A1 | |
| SCHEMBL7759912 | 0.80 | NOX4 (0.34) | NOX4DAOHPGDGRIN1ALDH1A1 | |
| SCHEMBL6087068 | 0.79 | DAO (0.46) | DAOHPGDALDH1A1KDM4ETLR7 | |
| SCHEMBL8071853 | 0.79 | ALDH1A1 (0.54) | DAOHPGDALDH1A1KDM4ETLR7 | |
| SCHEMBL12829055 | 0.79 | MAOB (0.36) | ALDH1A1KDM4E | |
| SCHEMBL7753910 | 0.79 | NOX4 (0.34) | NOX4DAOHPGDGRIN1ALDH1A1 | |
| SCHEMBL6087484 | 0.78 | GRIN1 (0.43) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |