Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852868 | 0.93 | PIK3R1 (0.39) | GRIN1GRIN2BPIK3R1PIK3CAGRM5 | |
| SCHEMBL6086817 | 0.85 | HPGD (0.43) | KMT2A | |
| SCHEMBL6087695 | 0.85 | GRIN1 (0.44) | GRIN1GRIN2BPIK3R1PIK3CAGRM5 | |
| SCHEMBL6086447 | 0.85 | MTNR1A (0.49) | GRIN1GRIN2BPIK3R1PIK3CAKMT2A | |
| SCHEMBL6087128 | 0.84 | TPH1 (0.34) | GRIN1GRIN2BKMT2A | |
| SCHEMBL6087068 | 0.84 | DAO (0.46) | KMT2A | |
| SCHEMBL6086571 | 0.82 | GRIN1 (0.49) | GRIN1GRIN2B | |
| SCHEMBL6086860 | 0.81 | ALDH1A1 (0.37) | KMT2A | |
| SCHEMBL1484799 | 0.81 | KCNH2 (0.39) | GRM5KMT2A | |
| SCHEMBL6087689 | 0.80 | GRIN1 (0.40) | GRIN1GRIN2BPIK3R1PIK3CAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |