Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345921 | 0.75 | LMNA (0.41) | ALDH1A1SMN1; SMN2HPGDLMNASLC6A2 | |
| SCHEMBL8607275 | 0.74 | CHAT (0.39) | ALDH1A1TSHRMEN1KMT2ACHAT | |
| Hydrochloric Acid SCHEMBL9052839 | 0.73 | CHAT (0.38) | ALDH1A1TSHRMEN1KMT2ACHAT | |
| SCHEMBL4940758 | 0.73 | CYP1A2 (0.45) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL8213720 | 0.72 | ALDH1A1 (0.36) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9811808 | 0.71 | ALDH1A1 (0.47) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9811807 | 0.70 | ALDH1A1 (0.49) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9508726 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TSHRCHATESR1 | |
| SCHEMBL7782968 | 0.68 | ALDH1A1 (0.43) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL8113061 | 0.67 | ALDH1A1 (0.46) | CYP1A2ALDH1A1SMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653633-B1 | Toxicity testing assay | UNIV OKLAHOMA STATE (US) | 2001-03-28 | — | — | EP | claimed |
| US-5834230-A | Viscosity Probe | MCGILL UNIVERSITY (CA) | 1998-11-10 | — | — | US | claimed |
| US-5834230-A | Viscosity Probe | MCGILL UNIVERSITY (CA) | 1998-11-10 | — | — | US | disclosed |