Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20887490 | 0.81 | CYP1A2 (0.47) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9811808 | 0.80 | ALDH1A1 (0.47) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL11128936 | 0.79 | CYP1A2 (0.46) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL8519976 | 0.79 | RAB9A (0.47) | CYP1A2ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL8113061 | 0.78 | ALDH1A1 (0.46) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL8213720 | 0.77 | ALDH1A1 (0.36) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL11206642 | 0.77 | NPC1 (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDAKR1C1 | |
| SCHEMBL12411252 | 0.77 | NPC1 (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDAKR1C1 | |
| SCHEMBL7717169 | 0.76 | CYP1A2 (0.50) | CYP1A2ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL8520463 | 0.76 | KDM4E (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240075017-A1 | TREATMENT OF CORONAVIRUS INFECTIONS USING SAM CYCLE INHIBITORS | UNIV MUENCHEN TECH (DE) | 2024-03-07 | — | — | US | claimed |
| EP-4304573-A1 | TREATMENT OF CORONAVIRUS INFECTIONS USING SAM CYCLE INHIBITORS | Technische Universität München (DE) | 2024-01-17 | — | — | EP | claimed |
| WO-2022189379-A1 | TREATMENT OF CORONAVIRUS INFECTIONS USING SAM CYCLE INHIBITORS | Technische Universität München (DE) | 2022-09-15 | — | — | WO | claimed |
| EP-0341720-B1 | Light-sensitive compositions | FUJI PHOTO FILM CO LTD (JP) | 1995-02-08 | — | — | EP | claimed |
| EP-0341720-A2 | Light-sensitive compositions | Fuji Photo Film Co., Ltd. (JP) | 1989-11-15 | — | — | EP | claimed |
| JP-57021401-A | — | — | None | — | — | JP | disclosed |
| US-20240075017-A1 | TREATMENT OF CORONAVIRUS INFECTIONS USING SAM CYCLE INHIBITORS | UNIV MUENCHEN TECH (DE) | 2024-03-07 | — | — | US | disclosed |
| CN-117597125-A | Indole-substituted quinolines and their use in combination with PLK1 inhibitors for the treatment of cancer | 肯塔基大学研究基金会 | 2024-02-23 | — | — | CN | disclosed |
| EP-4304573-A1 | TREATMENT OF CORONAVIRUS INFECTIONS USING SAM CYCLE INHIBITORS | Technische Universität München (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-11872230-B2 | Method of treating a methionine-dependent cancer | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2024-01-16 | — | — | US | disclosed |
| US-11851391-B2 | Antifungal compounds and methods of forming the same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-12-26 | — | — | US | disclosed |
| WO-2023107507-A1 | DIAMINOBUTOXY-SUBSTITUTED ISOFLAVONOIDS AS MITOCHONDRIAL COMPLEX I INHIBITORS FOR CANCER TREATMENT | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-06-15 | — | — | WO | disclosed |
| US-5998496-A | ABSORBING RADIATION | SPECTRA GROUP LIMITED, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0871607-A4 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LTD INC (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0871607-A1 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LIMITED INC (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997016406-A1 | PHOTOSENSITIVE INTRAMOLECULAR ELECTRON TRANSFER COMPOUNDS | SPECTRA GROUP LIMITED, INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0341720-B1 | Light-sensitive compositions | FUJI PHOTO FILM CO LTD (JP) | 1995-02-08 | — | — | EP | disclosed |
| US-5262276-A | Free radical polymerizable unsaturated compound and light-free radical | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0341720-A2 | Light-sensitive compositions | Fuji Photo Film Co., Ltd. (JP) | 1989-11-15 | — | — | EP | disclosed |
| JP-S5721401-A | PHOTOPOLYMERIZABLE COMPOSITION | MITSUBISHI CHEM IND LTD | 1982-02-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11872230-B2 | Method of treating a methionine-dependent cancer | MGMT, BHMT2, MTR | CYP1A2 1795/4885ALDH1A1 188/4885SMN1; SMN2 1915/4885 |
| US-11851391-B2 | Antifungal compounds and methods of forming the same | DPM1, ERG28, SUCLG1 | CYP1A2 59/4885ALDH1A1 1237/4885SMN1; SMN2 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.