SCHEMBL7758319

SCHEMBL7758319

CC(C)C(N)(CC(c1ccccc1)c1cc(CO[Si](C)(C)C)ccc1O[Si](C)(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758332 0.89 CHRM2 (0.31) CHRM2CHRM1
SCHEMBL2167555 0.78 CHRM2 (0.54) CHRM2CHRM1
SCHEMBL9220687 0.74 CHRM2 (0.43) CHRM2CHRM1
SCHEMBL3779737 0.74 ELANE (0.44) CHRM2CHRM1
SCHEMBL6757054 0.73 CHRM2 (0.52) CHRM2CHRM1
SCHEMBL6761854 0.73 CHRM2 (0.42) CHRM2CHRM1
SCHEMBL6760711 0.72 CHRM2 (0.42) CHRM2CHRM1
SCHEMBL3772904 0.72 ALOX15 (0.41) CHRM2CHRM1
SCHEMBL724361 0.70 CCR5 (0.48)
SCHEMBL2781332 0.70 KMT2A (0.39) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077912-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 2001-02-28 EP disclosed
WO-1999058478-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 1999-11-18 WO disclosed